Difference of high blood pressure hypertension
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High blood pressure or hypertension? You understand the difference, and protect your health! Many people hear the terms hypertension and hypertension and to think, it was two different diseases. But what's the difference really? Short and clear: There is no! High blood pressure is the colloquial name, while hypertension is the medical term. Both describe the same condition: a persistently elevated blood pressure increases the risk for heart attack, stroke, and kidney damage significantly. Why is it important to know? A hidden enemy: hypertension often shows a long time, no clear symptoms. That is why it is also called the silent Killer. However, any unhandled increase in blood pressure burden your heart and blood vessels. What can you do? Regular checks: measure your blood pressure regularly at home or at the doctor. A normal value is around 120/80 mmHg. Healthy lifestyle: a Balanced diet with little salt, regular physical activity, not Smoking and moderate alcohol consumption help to keep the blood pressure in the healthy range. Expert advice: In the case of persistently elevated values, you immediately talk to your doctor. He can recommend the right treatment, whether through lifestyle changes or medicines. Your health center – your Partner for a healthy life Our expert Doctors are available for you for a comprehensive consultation and diagnostics available. We offer: modern blood pressure measurements; customized prevention concepts; long-term care in hypertension. Appointment and protecting her heart! Call now or send us an E‑Mail. Make – your body will thank you for it!
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Non-infectious diseases of the cardiovascular Diabetes mellitus
Technology in the prevention of cardiovascular diseases
Medicines for high blood pressure the elderly
Professional Cardiovascular Diseases
http://www.spb-03.com/articles/50402-physical-therapy-in-cardiovascular-diseases.html
http://news.gorvetstan.beget.tech/articles/44358-cardiovascular-disease-in-simple-words.html
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New drugs against high blood pressure: progress and prospects High blood pressure, known medically as hypertension, is a worldwide health problem and is considered to be one of the main risk factors for cardiovascular diseases such as heart attack, stroke, and kidney damage. According to estimates by the world health organization (WHO) affects about one billion people worldwide have hypertension. The development of new drugs for the effective reduction of blood pressure is therefore of high clinical and social relevance. Current Therapy Approaches Traditional treatment strategies include various drug classes: ACE inhibitors (eg, Enalapril), which inhibit the formation of Angiotensin II; AT1‑receptor blockers (e.g., Losartan), which prevent the action of Angiotensin II to its receptors; Beta-blockers (e.g., Metoprolol), the lower the heart rate and force; Calcium channel blockers (e.g. amlodipine), which relax the smooth muscles of the blood vessels; Diuretics (such as hydrochlorothiazide) to reduce the liquid content in the body. In spite of this wide range of options that are resistant hypertension) remains a part of the patient's blood pressure is adequately controlled (or unwanted side effects. This motivates the search for new drugs. Latest Developments In the last few years, several innovative approaches have been developed: Endothelin‑receptor antagonists (e.g., Bosentan): they inhibit the effect of the strong Vasoconstrictor Endothelin‑1 and the show, especially in the case of special forms of hypertension (for example, in the case of chronic renal insufficiency), with promising results. Renin inhibitors (such as Aliskiren): By direct inhibition of the enzyme Renin, the whole of the Renin‑Angiotensin‑aldosterone System is broken‑cascade at an early stage. Studies show an effective reduction in blood pressure, however, must be evaluated in long-term data on safety more. Vasopeptidase inhibitors: Combined inhibition of Neprilysin (an enzyme that natriure degrades tables peptides) and ACE. This dual effect leads to greater vasodilation and Natriuresis. Immune therapeutic approaches: Experimental studies of antibodies against Angiotensin II or its receptors to investigate. This could allow a long-lasting blood pressure control. Gene and RNA‑based therapies: approaches to targeted inhibition of the Expression of blood pressure‑regulating proteins (e.g. by means of siRNA against AGTR1) are in preclinical phases. Clinical trials and effectiveness Several Phase III trials confirm the efficacy of new substances: In patients with resistant hypertension, the Addition of a Renin‑Inhibitor resulted in a significant reduction in systolic blood pressure by an average of 15.2 mmHg in comparison to the placebo group (p<0,001). Endothelin‑antagonists reduced the mean pulmonary arterial pressure in patients with pulmonary hypertension significantly (to be -10.3 mmHg, 95% CI: -13.1 with to -7.5). Challenges and future prospects Although these new drugs are promising, there are challenges: possible side effects (e.g., Hyperkalemia in Renin inhibitors); high costs in comparison to established therapies; Need for long-term data for the reduction of cardiovascular endpoints. The future of hypertension therapy is located in the personalization: Genetic testing that might allow prediction of individual efficacy and tolerability say. In addition, innovative delivery systems (for example, implants for continuous drug release) to open up new opportunities to improve therapy adherence. Conclusion The development of new drugs against high blood pressure expands the therapeutic options, and it provides patients with resistant or difficult-to-use yet hypertension, a new hope. Interdisciplinary research and innovative technologies will continue to drive progress in this area.